Two new indole alkaloids, 20-epi-antirhine [4] and 13(S)-hydroxydihydr
ocorynantheol [6], have been isolated from Antirhea portoricensis (Rub
iaceae), collected in the Caribbean. Structures have been established
on the basis of spectral data. In addition, four known alkaloids have
been isolated, namely, yohimbol [1], epi-yohimbol [2], antirhine [3] a
nd iso-antirhine [5].