Background Because of the inability of fluoroscopy to image intracardi
ac structures, the precise anatomic location of successful slow pathwa
y (SP) ablation is controversial. We hypothesized that adjunctive intr
acardiac echocardiography (ICE) in concert With conventional fluorosco
py and electrogram guidance could identify the anatomic site of succes
sful SP ablation. Methods and Results In 25 patients, radiofrequency a
blation was performed in the triangle of Koch directed by biplane fluo
roscopy and a 6.2F, 12.5-MHz ICE catheter positioned adjacent to the t
riangle of Koch. Persistent SP conduction, number of radiofrequency ap
plications, presence of junctional tachycardia, and fluoroscopy times
were evaluated. As demonstrated by ICE, anterograde SP ablation was ac
hieved between 2 and 7 mm from the tricuspid valve in imaging planes c
ontaining the AV muscular septum in all cases. Radiofrequency energy a
pplications applied at other sites within the triangle of Koch failed
to interrupt SP conduction. A mean of three radiofrequency energy appl
ications (3+/-2; range, 1 to 12) successfully ablated all evidence of
anterograde SP conduction in all patients studied. Junctional tachycar
dia was seen in 96% (71/74) of the radiofrequency energy applications.
Conclusions Radiofrequency ablation at the tricuspid valve's insertio
n into the AV muscular septum as identified by ICE reliably terminates
anterograde SP conduction, supporting the hypothesis that the SP cons
istently traverses this anatomic location.