Potential risk factors for inguinal hernia in women were investigated
and the relative importance of these factors was quantified. In women,
symptomatic but nonpalpable hernias often remain undiagnosed. However
, knowledge on this subject only concerns hernia and operation charact
eristics, which have been obtained by review of case series. Virtually
nothing is known about risk factors for inguinal hernia. The authors
performed a hospital-based case-control study of 89 female patients wi
th an incident inguinal hernia and 176 age-matched female controls. Ac
tivity since birth with two validated questionnaires was measured and
smoking habits, medical and operation history, Quetelet index (kg/m(2)
), and history of pregnancies and deliveries were recorded. Response f
or cases was 81% and for controls 73%. Total physical activity was not
associated with inguinal hernia (univariate odds ratio (OR) = 0.8, 95
% confidence interval (CI) 0.6-1.1), but high present sports activitie
s was associated with less inguinal hernia (multivariate OR = 0.2, 95%
CI 0.1-0.7). Obesity (Quetelet index >30) was also protective for ing
uinal hernia (OR = 0.2, 95% CI 0.04-1.0). Independent risk factors wer
e positive family history (OR = 4.3, 95% CI 1.9-9.7) and obstipation (
OR = 2.5, 95% CI 1.0-6.7). In particular, smoking, appendectomy, other
abdominal operations, and multiple deliveries were not associated wit
h inguinal hernia in females. The protective effect of present sports
activity may be explained by optimizing the resistance of the abdomina
l musculature protecting the relatively small inguinal weak spot in th
e female. The individual predisposition for inguinal hernia may be qua
ntified by these risk factors, and, with this in mind, the authors adv
ise that further evaluation might be needed for the patient with unexp
lained inguinal pain.