The use of incremental cost-outcomes ratios as decision variables by t
hose working in the area of pharmacoeconomics is commonplace. Unfortun
ately, few question the assumptions implicit in the use of such ratios
. In this paper, the author argues that under certain reasonable assum
ptions regarding the production of health care and alternative therapy
options, if partial substitution or switching between therapy options
occurs, it may be possible not only to stay within an initial health
care budget but also to yield higher total outcomes for the treating p
opulation. This argument is presented by developing a model of health
care costs and outcomes in a dual-therapy environment.