En. Liatsikos et al., LICHEN-SCLEROSUS-ET-ATROPHICUS - FINDINGS AFTER COMPLETE CIRCUMCISION, Scandinavian journal of urology and nephrology, 31(5), 1997, pp. 453-456
We prospectively evaluated 75 patients, 30-77 years old, with severe p
himosis. All patients were treated surgically by complete circumcision
and all surgical specimens were sent for histological evaluation. All
patients with histologically proven lichen sclerosus et atrophicus (L
SA) (eight patients, 10.6%) were re-evaluated 6 months postoperatively
, and ail but one were examined 5 years after the operation. All patie
nts with histologically proven balanoposthitis (BP) (47 patients, 62.6
%) were also re-evaluated 6 months postoperatively, and 41 patients 5
years after surgery. This group (BP) was the control group of our stud
y. Six months after the operation, the eight patients with histologica
lly proven LSA all had an excellent convalescence, and the lesions obs
erved during the operation resolved in four patients and regressed in
two patients. In one patient the glans presented with a pale grey-whit
e-coloured plaque. Biopsy was performed and a well-differentiated squa
mous cell carcinoma infiltrating the glans was revealed. The control g
roup of patients with histologically proven BP were also re-evaluated
6 months and 5 years after surgery. An excellent convalescence was obs
erved in all patients who completed the follow-up examination. Care mu
st be taken not to underestimate the potential relationship between LS
A and squamous cell carcinoma, because the latter is usually invasive,
very aggressive and requires immediate treatment.