Postcatheterization injuries at the vascular access site include pseud
oaneurysms and arteriovenous fistulas. Traditional treatment of this c
omplication has been surgical repair. This study describes a recently
developed method for closing femoral pseudoaneurysms and arteriovenous
fistulas by using external compression guided by Doppler color flow i
maging. Thirty-six femoral artery injuries (31 pseudoaneurysms, 5 arte
riovenous fistulas) were detected by color flow imaging in 35 patients
with enlarging groin hematomas and/or groin bruits. All patients unde
rwent a full trial of compression therapy, with an extended compressio
n time limit of 240 minutes and a tag-team approach of two operators t
o overcome manual fatiguing. The mechanical compression was titrated t
o obliterate the vascular tracts to the aneurysms or of the arterioven
ous fistulas and to maintain an adequate flow in the femoral artery, a
s far as possible. All postangiographic pseudoaneurysms were successfu
lly treated with a compression time ranging from 10 to 110 minutes, ev
en in patients receiving prolonged anticoagulant therapy. Follow-up ul
trasound examination the following morning and 4 to 5 days later confi
rmed a continued closure in all patients, without side effects such as
venous thrombosis or ischemia. In arteriovenous fistulas, compression
therapy was successful in two cases without complications or recurren
ces during follow-up. This study demonstrates that Doppler color flow
ultrasound-guided compression of postangiographic femoral artery injur
ies is a safe and technically simple device and may be implemented as
a cost-effective, first-line treatment, with a high rate of success in
pseudoaneurysms.