Objective: This experiment tested the impairing effect of alcohol on c
ognitive inhibitory control of behavior in the absence of any motivati
onal consequences for exhibiting or inhibiting a response. Method: Men
(n = 24) and women (n = 24) were trained on a computerized ''go-stop'
' task that measured response reaction time (RT) to a go signal and in
hibitory control by the number of inhibitions to a randomly occurring
stop signal. Equal numbers of men (n = 8) and women (n = 8) were assig
ned to one of three groups (n = 16), and they performed the task alone
in a room under either alcohol (A), placebo (P) or no-treatment contr
ol (C) conditions. Blood alcohol concentrations of men and women were
matched in Group A by administering 0.62 and 0.54 g/kg of alcohol, res
pectively. Results: Alcohol impaired inhibitory control and had no sig
nificant effect on response RT. Under P and C conditions, no changes i
n inhibitions or response RT were observed. In addition, no significan
t gender effects were found. Conclusions: The results showed that inhi
bitory control of behavior was impaired by a moderate dose of alcohol
that did not affect response RT.