DIFFERENCE IN P300 LATENCY IN 2 TYPES OF LEUKOARAIOSIS

P300 examination was performed in patients with periventricular leukoa raiosis and in patients with leukoaraiosis in die centrum semiovale. T en patients with periventricular leukoaraiosis, ten patients with leuk oaraiosis in centrum semiovale and ten age-matched controls without le ukoaraiosis were studied. The P300 was measured with an evoked potenti al recorder using an oddball paradigm. The mini-mental state examinati on score was significantly lower and the P300 latency was significantl y longer in the leukoaraiosis in the centrum semiovale group than in t he periventricular leukoaraiosis group and the control group. Leukoara iosis in centrum semiovale may be related to dementia and the prolonga tion of P300 latency.