BALHIMYCIN, A NEW GLYCOPEPTIDE ANTIBIOTIC PRODUCED BY AMYCOLATOPSIS SP Y-86,21022 - TAXONOMY, PRODUCTION, ISOLATION AND BIOLOGICAL-ACTIVITY

Authors
NADKARNI SR PATEL MV CHATTERJEE S VIJAYAKUMAR EKS DESIKAN KR BLUMBACH J GANGULI BN LIMBERT M
Citation
Sr. Nadkarni et al., BALHIMYCIN, A NEW GLYCOPEPTIDE ANTIBIOTIC PRODUCED BY AMYCOLATOPSIS SP Y-86,21022 - TAXONOMY, PRODUCTION, ISOLATION AND BIOLOGICAL-ACTIVITY, Journal of antibiotics, 47(3), 1994, pp. 334-341
Citations number
8
Categorie Soggetti
Pharmacology & Pharmacy",Immunology
Journal title
Journal of antibiotics → ACNP
ISSN journal
00218820
Volume
47
Issue
3
Year of publication
1994
Pages
334 - 341
Database
ISI
SICI code
0021-8820(1994)47:3<334:BANGAP>2.0.ZU;2-Y
Abstract
A new glycopeptide antibiotic, balhimycin, has been isolated from the fermentation broth of a Amycolatopsis sp. Y-86,21022. Balhimycin belon gs to the vancomycin class of glycopeptides and contains a dehydrovanc osamine sugar. The biological activity of balhimycin has been compared extensively with that of vancomycin against methicillin resistant sta phylococci and also against anaerobes. Balhimycin is marginally superi or to vancomycin in its in vitro activity against anaerobes and in its bactericidal properties.