Thalamic tumors (TT) merit individual analysis and must not be confuse
d with tumors that, while involving the entire thalamus have a differe
nt origin. We analyzed 26 patients who fulfilled our criteria of havin
g ''strictly'' TT. We examined incidence, clinical features, histology
, response to treatment (mainly surgery), recurrence rate, mortality a
nd prognosis. We considered that histology and surgical treatment were
the most important items related to prognosis. Low-grade tumors (LGT)
had a good prognosis, while anaplastic tumors (AT) had a discouraging
one; nevertheless both must be operated on. We believe that total rem
oval of LGT is curative and total removal of AT, even if it is not cur
ative, can extend survival by some months. Radiotherapy and chemothera
py seemed to be of little value in our series of TT.