To determine the sensitivity and clinical value of different diagnosti
c tools (CCT, EEG and SPECT) in patients with acute ischemic stroke. T
he subjects were 80 unselected patients with acute supratentorial cere
bral ischemia. 25 patients suffered from TIAs, 19 patients from lacuna
r infarction and 36 patients from watershed, terminal and territorial
infarction. In the first 36 hours after the onset of symptoms, CCT (n=
80), EEG (n=79) and SPECT (n=64) procedures were performed. A second C
CT was undertaken in 70 cases 3 or 4 days later to demonstrate potenti
al substantial lesion. The sensitivities of the methods for the recogn
ition of a lateralized hemispheric disorder were evaluated and statist
ically compared. In large cortical infarctions (watershed, terminal or
territorial infarction) the cerebral dysfunction was recognised in 10
0% of cases by EEG and SPECT. In lacunar infarction EEG demonstrated p
athologic abnormalities in 73.7% and SPECT in 52.6%. In TIAs EEG revea
led abnormalities in 41.7% and SPECT only in 9.5%; these differences w
ere statistically significant (Me Nemar test; p- 0,0309). Zed CCT was
goldstandard (sensitivity 100%) for the evaluation of a substantial le
sion in lacunar and large cortical infarction. In TIAs and lacunar inf
arction EEG is superior to SPECT for the recognition of a lateralized
supratentorial cerebral ischemia. In large cortical infarction both me
thods show equal sensitivities. In the early phase of cerebral ischemi
a both methods are able to demonstrate cerebral disorder at a time whe
n CCT is mostly unremarkable. SPECT seems to differentia more precisel
y in the early phase between minor and major stroke consequences.