A. Ghezzi et al., CEREBRAL INVOLVEMENT IN CELIAC-DISEASE - A SERIAL MRI STUDY IN A PATIENT WITH BRAIN-STEM AND CEREBELLAR SYMPTOMS, Neurology, 49(5), 1997, pp. 1447-1450
A patient with celiac disease and relapsing-progressive symptoms sugge
sting brainstem and cerebellar involvement underwent serial MRIs. The
first examination revealed multiple enhancing and nonenhancing lesions
. Thereafter, a large enhancing cerebellar lesion appeared, followed b
y severe cerebellar atrophy. The presence of structural neuronal damag
e was confirmed by proton MR spectroscopy and magnetization transfer i
maging. MRI results and CSF findings suggested that neurologic complic
ations were more likely due to an inflammatory process.