A NEW ASYMMETRIC BRIDGING ANNULATION REACTION INVOLVING THE INTRAMOLECULAR MICHAEL ADDITION OF CHIRAL IMINES TO ENOATES

Authors
DUMAS F MAINE V CAVE C DANGELO J
Citation
F. Dumas et al., A NEW ASYMMETRIC BRIDGING ANNULATION REACTION INVOLVING THE INTRAMOLECULAR MICHAEL ADDITION OF CHIRAL IMINES TO ENOATES, Tetrahedron : asymmetry, 5(3), 1994, pp. 339-342
Citations number
3
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
3
Year of publication
1994
Pages
339 - 342
Database
ISI
SICI code
0957-4166(1994)5:3<339:ANABAR>2.0.ZU;2-G
Abstract
Thermal cyclization of imine 12b led,after hydrolytic work-up, to bicy clic derivative 13b with a very high control of the three newly create d stereogenic centers. In contrast adducts 13a and 13c, resulting from the cyclization of imines 12a and 12c respectively, were obtained as complex mixtures of stereomers.