We have observed 5 infants who demonstrate normal breathing when awake
, but develop stridor while asleep. Flexible laryngoscopy in the awake
state reveals either a normal larynx or redundancy of the aryepiglott
ic folds or arytenoid soft tissue without prolapse into the laryngeal
inlet. When these children are sedated, however, the classic signs of
laryngomalacia appear. Wet inspiratory strider with concomitant suprag
lottic prolapse can be demonstrated by flexible videolaryngoscopy in t
his state. As these findings vary with level of consciousness, we have
dubbed this condition ''state-dependent'' laryngomalacia. We believe
the appearance and disappearance of classic laryngomalacia with change
s in level of consciousness adds credence to the neurogenic theory of
laryngomalacia.