Cervical necrotizing fasciitis (CNF) is an aggressive infection of the
head and neck with high complication and mortality rates. Sixty-eight
cases of CNF have been reported in the English-language literature. W
e present a series of 8 patients with CNF, including 5 men and 3 women
ranging in age from 25 to 92 years. To the best of our knowledge, thi
s is one of the largest case series reported. Six of the 8 patients ha
d a predisposing odontogenic focus of infection. Four patients had med
iastinal involvement. Two patients, both with significant comorbidity
at the time of presentation, died of CNF.