REVERSIBLE ACTIVE-SITE PROTONATION AND ELECTRON-TRANSFER PROPERTIES OF ACHROMOBACTER CYCLOCLASTES PSEUDOAZURIN - COMPARISONS WITH OTHER TYPE-1 COPPER PROTEINS

Authors
DENNISON C KOHZUMA T MCFARLANE W SUZUKI S SYKES AG
Citation
C. Dennison et al., REVERSIBLE ACTIVE-SITE PROTONATION AND ELECTRON-TRANSFER PROPERTIES OF ACHROMOBACTER CYCLOCLASTES PSEUDOAZURIN - COMPARISONS WITH OTHER TYPE-1 COPPER PROTEINS, Journal of the Chemical Society, Chemical Communications, (5), 1994, pp. 581-582
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
5
Year of publication
1994
Pages
581 - 582
Database
ISI
SICI code
0022-4936(1994):5<581:RAPAEP>2.0.ZU;2-W
Abstract
Kinetic and NMR studies on the copper(I) form of A. cycloclastes pseud oazurin provide evidence for an active site protonation (and dissociat ion) equilibrium process involving His81, pK(a) 4.9 (average); the thr ee type 1 copper proteins now known to exhibit this behaviour have jus t two amino acids separating the ligating Cys and His residues in the C-terminal region.