INDUCTION OF GLUTATHIONE-S-TRANSFERASE ACTIVITY IN TRIATOMA-INFESTANS

Citation
Jl. Sivori et al., INDUCTION OF GLUTATHIONE-S-TRANSFERASE ACTIVITY IN TRIATOMA-INFESTANS, Memorias do Instituto Oswaldo Cruz, 92(6), 1997, pp. 797-802
Citations number
38
Categorie Soggetti
Tropical Medicine
ISSN journal
00740276
Volume
92
Issue
6
Year of publication
1997
Pages
797 - 802
Database
ISI
SICI code
0074-0276(1997)92:6<797:IOGAIT>2.0.ZU;2-C
Abstract
Several synthetic pesticides and allelochemicals used to treat Triatom a infestans adults by topic application showed some degree of cytosoli c glutathione S-transferase (GST) induction. General inducers of detox ication systems such as phenobarbital and 3-methylcholantrene topicall y applied on T. infestans resulted in no GST induction. Meanwhile, gen eral insecticide synergist such as piperonyl butoxide (160 mu g/insect ) increased the GST-activity in the range of 120-140%. Insects injecte d with reduced glutathione (300 mg/insect) presented at the forth day elevated GST activity.