MYELOPEROXIDASE-ANTINEUTROPHIL CYTOPLASMIC ANTIBODY-ASSOCIATED GLOMERULONEPHRITIS WITH MEMBRANOUS NEPHROPATHY IN REMISSION

A 47-year-old woman developed pulmonary hemorrhage and an increase in proteinuria during remission of membranous nephropathy. Renal biopsy r evealed crescentic glomerulonephritis. She also had a high perinuclear antineutrophil cytoplasmic antibody level, so a diagnosis of myeloper oxidase-antineutrophil cytoplasmic antibody-associated glomerulonephri tis was made. After immunosuppressive therapy was started, the pulmona ry hemorrhage resolved and her proteinuria decreased. Renal biopsy was repeated after treatment and showed histological improvement. This ca se suggests that there may be a relationship between membranous nephro pathy and myeloperoxidase-antineutrophil cytoplasmic antibody-associat ed glomerulonephritis.