From 1994 to March 1997, 12 patients with 15 drug-related abscesses of
the groin were treated at the Surgical Department of Lubeck Medical U
niversity. Besides laboratory, serological and microbiological examina
tions, the standard diagnostic investigation consisted of sonography o
r duplex sonography. If indicated, the diagnosis was extended to inclu
de, for example, clarification of the retroperitoneum by CT. The most
common accompanying disease was deep femoral vein thrombosis. Substitu
tion was planned individually. After surgical debridement and perioper
ative administration of a beta-lactam-protected acylaminopenicillin, o
pen wound treatment was successfully carried out in 13 cases; secondar
y closure was performed four times in cases of good compliance. One ab
scess led to necrotising of the femoral artery; saphenous vein was int
erposed because of erosion bleeding and formation of aneurysm. In a se
cond case, the bifurcation was reconstructed with saphenous vein after
external resection of an infected false aneurysm and early occlusion.
Both defects were covered by rotation of sartorius muscle and mesh gr
aft. On the basis of the treatment concept, a rapid and successful int
ervention was possible; complications such as sepsis, amputation or wi
thdrawal delirium did not occur. Resistance against the antibiotic was
not observed. In the case of infected aneurysm, we prefer the autogen
ous saphenous vein graft followed by rotation of sartorius muscle and
mesh graft. Ligation or excision leads to high rates of claudication o
r amputation; extended reconstructions are threatened by insufficient
compliance of the patients; the use of synthetic grafts is endangered
by further bacteraemia or infections.