EVIDENCE FOR ROLLING CIRCLE REPLICATION OF AUTOGRAPHA-CALIFORNICA M-NUCLEOPOLYHEDROVIRUS GENOMIC DNA

Citation
Di. Oppenheimer et Le. Volkman, EVIDENCE FOR ROLLING CIRCLE REPLICATION OF AUTOGRAPHA-CALIFORNICA M-NUCLEOPOLYHEDROVIRUS GENOMIC DNA, Archives of virology, 142(10), 1997, pp. 2107-2113
Citations number
18
Categorie Soggetti
Virology
Journal title
ISSN journal
03048608
Volume
142
Issue
10
Year of publication
1997
Pages
2107 - 2113
Database
ISI
SICI code
0304-8608(1997)142:10<2107:EFRCRO>2.0.ZU;2-7
Abstract
Antographa californica M nucleopolyhedrovirus (AcMNPV) is a large ds D NA virus restricted to larval lepidopteran insect hosts. Using field i nversion gel electrophoresis and digestion with a restriction enzyme w hich cuts the AcMNPV genome once, we detected multiple unit-length gen ome fragments from replicating viral DNA. Our data suggest that AcMNPV replicates in a head-to-tail manner via rolling circle replication.