Background Vitrectomy serves as an important treatment modality in uve
itis, removing inflamed vitreous body and eliminating secondary compli
cations. The aim of our retrospective study was to evaluate the value
of vitrectomy in the treatment of complications in uveitis. Patients a
nd method We included 50 eyes of 50,patients suffering from chronic uv
eitis, which underwent vitrectomy surgery during the period of 1990 to
1993. The study only included patients who had vitrectomy for uveitis
for the first time. Indications leading to surgery were density of op
tic media, retinal detachment, cyclitic or preretinal membranes. The m
ean follow-up was 455 (range 48-1420) days. Results Vitrectomy was per
formed ata mean delay of 452 days after initial presentation. The mean
visual acuity at the time of surgery was 0,05. The best visual acuity
postoperatively was measured at a mean time of 118 days after vitrect
omy. Overall, at the last control, eyes with preoperative retinal deta
chment presented a much worse final functional result (visual acuity o
f 0,02) than eyes without detachment (visual acuity of 0,5). Ten eyes
resulted in hypotonia after surgery (7 eyes with persisting hypotonia)
. Most frequent complications in the postoperative course were macular
pucker (11 eyes), secondary glaucoma (10 eyes), macular edema (6 eyes
) and retinal detachment (6 eyes). Fifty percent of all complications
occurred within the first 3 months following surgery. Conclusion Vitre
ctomy leads to a permanent increase in visual acuity through the treat
ment of complications, on the condition that a stable retinal situatio
n was present preoperativly.