D. Bankaitisdavis et al., OLIGONUCLEOTIDE PHOSPHONATES - SOLID-PHASE SYNTHESIS AND BIOCHEMICAL-CHARACTERIZATION, Nucleosides & nucleotides, 16(7-9), 1997, pp. 945-949
A novel method for the automated synthesis of oligonucleotide-3'phosph
onates is described. Oligonucleotide analogs synthesized by this metho
d exhibited appreciable stability to exonuclease digestion.