SYNTHESIS AND PROPERTIES OF OLIGORIBONUCLEOTIDE ANALOGS HAVING AMIDE (3'-CH2-CO-NH-5') INTERNUCLEOSIDE LINKAGES

Authors
ROZNERS E STROMBERG R
Citation
E. Rozners et R. Stromberg, SYNTHESIS AND PROPERTIES OF OLIGORIBONUCLEOTIDE ANALOGS HAVING AMIDE (3'-CH2-CO-NH-5') INTERNUCLEOSIDE LINKAGES, Nucleosides & nucleotides, 16(7-9), 1997, pp. 967-970
Citations number
14
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
16
Issue
7-9
Year of publication
1997
Pages
967 - 970
Database
ISI
SICI code
0732-8311(1997)16:7-9<967:SAPOOA>2.0.ZU;2-E
Abstract
Amide linked ribonucleoside dimer 5 was prepared and converted into se lectively protected H-phosphonate building block 9. Oligoribonucleotid e duplexes having amide linkages at selected sites were synthesized an d their stability was studied by UV melting experiments.