SYNTHESIS AND CYTOTOXIC ACTIVITY OF SELENOPHENFURIN, A NEW INHIBITOR OF IMP DEHYDROGENASE

Authors
CAPPELLACCI L FRANCHETTI P ABUSHEIKHA G JAYARAM HN GURUDUTT VV SINT T SCHNEIDER BP GOLDSTEIN BM PERRA G POMA S LACOLLA P GRIFANTINI M
Citation
L. Cappellacci et al., SYNTHESIS AND CYTOTOXIC ACTIVITY OF SELENOPHENFURIN, A NEW INHIBITOR OF IMP DEHYDROGENASE, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1045-1048
Citations number
12
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
16
Issue
7-9
Year of publication
1997
Pages
1045 - 1048
Database
ISI
SICI code
0732-8311(1997)16:7-9<1045:SACAOS>2.0.ZU;2-H
Abstract
The synthesis of 5-beta-D-ribofuranosylselenophene-3-carboxamide (sele nophenfurin) is reported. Selenophenfurin was found active as cytotoxi c agent and as inosine monophosphate dehydrogenase inhibitor.