CONJUGATED ANTISENSE OLIGONUCLEOTIDES FOR INHIBITION OF HUMAN CYTOMEGALOVIRUS IN-VITRO

Authors
ZHANG ZD SMITH JA SMYTH AP EISENBERG W NICHOLS A PARI GS TANG JY
Citation
Zd. Zhang et al., CONJUGATED ANTISENSE OLIGONUCLEOTIDES FOR INHIBITION OF HUMAN CYTOMEGALOVIRUS IN-VITRO, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1169-1172
Citations number
6
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
16
Issue
7-9
Year of publication
1997
Pages
1169 - 1172
Database
ISI
SICI code
0732-8311(1997)16:7-9<1169:CAOFIO>2.0.ZU;2-D
Abstract
Several thiono triester containing oligonucleotide phosphorothioates l inked with a lipophilic group have been synthesized. Some of these mod ified antisense oligonucleotides show potent anti-HCMV activity as wel l as improved cellular association and nuclease resistance.