SUICIDE GENE-THERAPY FOR INTRINSICALLY DRUG-RESISTANT SOLID TUMORS

Authors
NELSON JA PAN BF MARINI FC
Citation
Ja. Nelson et al., SUICIDE GENE-THERAPY FOR INTRINSICALLY DRUG-RESISTANT SOLID TUMORS, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1251-1259
Citations number
26
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
16
Issue
7-9
Year of publication
1997
Pages
1251 - 1259
Database
ISI
SICI code
0732-8311(1997)16:7-9<1251:SGFIDS>2.0.ZU;2-J
Abstract
The failure of available anticancer drugs to cure the common human sol id tumors is thought to be caused by their poor selective toxicity. As demonstrated herein, suicide gene therapy offers the potential to imp rove selective toxicity.