SYNTHESIS AND IMP DEHYDROGENASE (TYPE-I AND TYPE-II) INHIBITORY ACTIVITY OF ISOSTERIC NAD ANALOGS DERIVED FROM THIOPHENFURIN AND FURANFURIN

Authors
FRANCHETTI P CAPPELLACCI L ABUSHEIKHA G JAYARAM HN SCHNEIDER BP SINT T GURUDUTT VV COLLART FR HUBERMAN E GRIFANTINI M
Citation
P. Franchetti et al., SYNTHESIS AND IMP DEHYDROGENASE (TYPE-I AND TYPE-II) INHIBITORY ACTIVITY OF ISOSTERIC NAD ANALOGS DERIVED FROM THIOPHENFURIN AND FURANFURIN, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1415-1418
Citations number
13
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
16
Issue
7-9
Year of publication
1997
Pages
1415 - 1418
Database
ISI
SICI code
0732-8311(1997)16:7-9<1415:SAID(A>2.0.ZU;2-C
Abstract
Thiophene-3-carboxamide adenine dinucleotide (TFAD), and furan-3-carbo xamide adenine dinucleotide (FFAD), two NAD analogs, were synthesized and evaluated as inhibitors of inosine monophosphate dehydrogenase typ e I and type II.