SYNTHESIS OF 3'-THIORIBOURIDINE, 3'-THIORIBOCYTIDINE, AND THEIR PHOSPHORAMIDITES

Authors
SUN SG PICCIRILLI JA
Citation
Sg. Sun et Ja. Piccirilli, SYNTHESIS OF 3'-THIORIBOURIDINE, 3'-THIORIBOCYTIDINE, AND THEIR PHOSPHORAMIDITES, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1543-1545
Citations number
8
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
16
Issue
7-9
Year of publication
1997
Pages
1543 - 1545
Database
ISI
SICI code
0732-8311(1997)16:7-9<1543:SO33AT>2.0.ZU;2-D
Abstract
3'-Thio-3'-deoxyribonucleosides (U and C) have been synthesized via Vo rbruggen-type glycosylation with 3-S-benzoyl-5-O-toluoyl-1,2-O-diacety lfuranose, which was obtained from 3-O-trifluoromethanesulfonyl-alpha- D-xylofuranose. 3'-Thio-3'-deoxyuridine has been converted to its phos phoramidite.