CONVENIENT METHOD FOR LABELING OLIGONUCLEOTIDE ANALOGS BY A FLUOROGENIC TAG FOR DIRECT IN-VITRO AND IN-VIVO VISUALIZATION OF CARBOXYESTERASE ACTIVITY

Authors
LAURENT A DEBARTVASSEUR F IMBACH JL RAYNER B
Citation
A. Laurent et al., CONVENIENT METHOD FOR LABELING OLIGONUCLEOTIDE ANALOGS BY A FLUOROGENIC TAG FOR DIRECT IN-VITRO AND IN-VIVO VISUALIZATION OF CARBOXYESTERASE ACTIVITY, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1765-1766
Citations number
6
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
16
Issue
7-9
Year of publication
1997
Pages
1765 - 1766
Database
ISI
SICI code
0732-8311(1997)16:7-9<1765:CMFLOA>2.0.ZU;2-2
Abstract
The synthesis of two oligonucleoside phosphorothioate and methylphosph onate analogs functionalized with a fluorogenic tag is described. The fluorescent conjugate formation is demonstrated in cell culture medium , cell extracts and in human fibroblasts.