SYNTHESIS OF A 2-HYDROXY-OXOLANE DERIVATIVE AS A NEW POTENTIAL CROSS-LINKING AGENT OF DNA

Authors
NZITA L LADAME S GOMEZ L MOREAU S
Citation
L. Nzita et al., SYNTHESIS OF A 2-HYDROXY-OXOLANE DERIVATIVE AS A NEW POTENTIAL CROSS-LINKING AGENT OF DNA, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1781-1784
Citations number
13
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
16
Issue
7-9
Year of publication
1997
Pages
1781 - 1784
Database
ISI
SICI code
0732-8311(1997)16:7-9<1781:SOA2DA>2.0.ZU;2-E
Abstract
The design and the synthesis of a new potential crosslinking agent of DNA is reported. It is based on the alkylating properties of a natural toxin (botryodiplodin) and will be further linked to antisense oligon ucleotides.