D. Richardson et al., THE EFFECT OF BOTULINUM TOXIN ON HAND FUNCTION AFTER INCOMPLETE SPINAL-CORD INJURY AT THE LEVEL OF C5 6 - A CASE-REPORT/, Clinical rehabilitation, 11(4), 1997, pp. 288-292
Objective: To investigate the benefits of the focal use of botulinum t
oxin in spasticity in the forearm seen after incomplete spinal cord in
jury. Design: A single case study with standardized assessment before
and al three-week intervals after injection. Intervention: EMG-guided
selective injection of botulinum toxin. Subject: A 23-year-old man, 18
months post injury. Measures: Rivermead Motor Assessment; grip streng
th; Jebsen hand tests; visual analogue scale; Ashworth spasticity scal
e. Results: Weakness was seen as expected with some functional losses,
but the patient made gains in the areas of concern: shaking hands, ty
ping, using the hand to drink. These gains were sustained at 12 weeks.
Conclusion: Selective use of botulinum toxin to weaken muscles can le
ad to functional benefit.