PRONY METHODS IN NMR-SPECTROSCOPY

The Prony method and a modified Prony method (MPM), developed to impro ve the performance of this technique at low signal-to-noise ratio, are described and applied to analysis of magnetic resonance spectroscopy (MRS) signals. Furthermore, the way in which results from MPM can be u sed as prior information in a Bayesian model is also described. First, analysis on simulated data is used to establish the methods' limits o f reliability. Their performance with respect to peak identification a nd quantification of nuclear magnetic resonance parameters are then as sayed on real data. Results of application of the methods to H-1-MRS s ignals from cultured cells are discussed and compared with those deriv ing from application of fast Fourier transform. (C) 1997 John Wiley & Sons, Inc.