KINETIC EVIDENCE FOR THE CONFORMATIONAL-CHANGES IN R(2), CIS-6-DIPHENYL-TRANS-3-TRANS-5-PIPERIDIN-4-ONE OXIME

Authors
YESUDIAN CD BENNY JCN NADAR PA
Citation
Cd. Yesudian et al., KINETIC EVIDENCE FOR THE CONFORMATIONAL-CHANGES IN R(2), CIS-6-DIPHENYL-TRANS-3-TRANS-5-PIPERIDIN-4-ONE OXIME, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 36(8), 1997, pp. 675-678
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
36
Issue
8
Year of publication
1997
Pages
675 - 678
Database
ISI
SICI code
0376-4699(1997)36:8<675:KEFTCI>2.0.ZU;2-4
Abstract
Kinetics of oxidation of substituted piperidin-4-one oximes 1-8 by tha llic acetate in aqueous acetic acid medium is followed iodometrically at 25 degrees, 30 degrees and 35 degrees C respectively. The order of the reaction with respect to oxime and oxidant has been found to be un ity in each case. The first order rate constants with respect to the o ximes are found to vary with the varying substituents in the heterocyc lic ring. A possible explanation has been given to account for the var iation in reactivity in terms of conformational changes on increasing the temperature.