We report the cases of two patients with adult-onset, simple, nonvaryi
ng tic disorder that commenced after a peripheral (non-CNS) injury. Th
e first patient is a 38-year-old man who suffered a right facial injur
y when his car fell off its jack while he was working underneath. Bila
teral facial twitching began hours after the trauma and was characteri
zed as a sniffinglike gesture. The movements waxed and waned, were sup
pressible, and were associated with a premonitory sensation. The ties
remitted after 9 months but still recur occasionally under stressful s
ituations. The second patient is a 34-year-old man with a 3-year histo
ry of abrupt, rapid head-turning movements that began 12 months after
a motor vehicle accident in which he injured his neck, The ties contin
ue to wax and wane, are suppressible, and are associated with an urge.
Neither patient suffered a head injury or had a family history of Tou
rette syndrome. Based on the clinical and historical features of these
patients, the temporal relationship between the trauma and onset of t
ies, and the occurrence of ties only in the traumatized region, a caus
al relationship is possible. These may represent the first reported ca
ses of tic disorder in association with peripheral injury. The mechani
sm by which the tic disorder resulted from the peripheral injury is un
clear, but these patients might have been susceptible individuals and
the trauma acted as a trigger.