Nm. Kaplan, BETA-BLOCKADE IN THE PRIMARY PREVENTION OF HYPERTENSIVE CARDIOVASCULAR EVENTS WITH FOCUS ON SUDDEN CARDIAC DEATH, The American journal of cardiology, 80(9B), 1997, pp. 20-22
Beta-adrenergic blocking agents are useful drugs in the treatment of h
ypertension. In multiple clinical trials, beta blockers have been foun
d to decrease the incidence of stroke and overall cardiovascular morta
lity. To provide maximal benefit, in particular, to blunt the early-mo
rning surge in blood pressure associated with the increased circadian
incidence of sudden cardiac death, the more cardioselective and longer
-acting agents of this drug class are preferred. (C) 1997 by Excerpta
Medica, Inc.