T. Aoki et al., BIOLOGICALLY-ACTIVE CLERODANE-TYPE DITERPENE GLYCOSIDES FROM THE ROOT-STALKS OF DICRANOPTERIS-PEDATA, Phytochemistry, 46(5), 1997, pp. 839-844
The molecular structure of the biologically active diterpene alcohol i
solated previously from the root-stalks of Dicranopteris pedata and Gl
eichenia japonica was confirmed to be (6S, 13S)-cleroda-3,14-diene-6,1
3-diol by an X-ray crystallographic analysis, together with applicatio
n of the octant rule to the Cotton effect observed in the CD spectrum
of its 6-keto derivative. Further investigation of the root-stalks of
D. pedata has resulted in the isolated two new glycosides, which were
characterised as (6S,13S)-6-O-[beta-D-glucopyranosyl- (1-->4)-alpha-L-
rhamnopyranosyl]-13-O-[alpha-L- anosyl-(1-->4)-beta-D-fucopyranosyl]-c
leroda-3,14- diene and -O-[beta-glucopyranosyl]-13-O-[beta-fucopyranos
yl- (1-->2)-alpha-rhamnopyranosyl]-cleroda-3,14-diene. Of these two gl
ycosides, the former glycoside accelerated the growth of the stems of
lettuce and inhibited the growth of the roots. (C) 1997 Elsevier Scien
ce Ltd.