A new neo-clerodane, 11-episcutecyprin has been isolated from the aeri
al parts of Scutellaria columnae var. columnae, in addition to the kno
wn diterpene scutegalin D. The structure of the new compound was estab
lished by spectroscopic means as (11R, 13R, 16S, 19R)-6 alpha-acetoxy-
4 alpha, 18; 11, 16,: 15,16-triepoxy neocleroda-(19-O-tigloyl)-19,2 al
pha-hemiacetal. The biogenesis of this compound is briefly discussed.
(C) 1997 Elsevier Science Ltd.