The 18-year-old white male driver and 17-year-old white male passenger
of an automobile were killed when their vehicle crossed the median of
a 4-lane highway and collided with a minivan. A can of airbrush prope
llant was found in the automobile of the deceased. The only drug detec
ted during initial toxicological analyses was 130 mg/L ethanol in the
blood of the driver. When performing ethanol analysis by headspace gas
chromatography, an unidentified peak was observed in the blood of bot
h deceased. This peak was identified as difluoroethane (Freon 152), th
e propellant in the aerosol can found in the automobile. The concentra
tions of difluoroethane in the blood of the driver and passenger were
78 mg/L and 35 mg/L, respectively. Based on a literature search we bel
ieve that this is the first report of the quantitation of difluoroetha
ne in biological samples.