K. Kroenke et al., DEPRESSIVE AND ANXIETY DISORDERS IN PATIENTS PRESENTING WITH PHYSICALCOMPLAINTS - CLINICAL PREDICTORS AND OUTCOME, The American journal of medicine, 103(5), 1997, pp. 339-347
PURPOSE: TO identify the predictors of depressive and anxiety disorder
s in general medical patients presenting with physical complaints and
to determine the effect of these mental disorders on patient outcome.
PATIENTS AND METHODS: In this cohort study, 500 adults presenting to a
general medicine clinic with a chief complaint of a physical symptom
were interviewed with PRIME-MD to diagnose DSM-IV depressive and anxie
ty disorders. Clinical predictors were identified by logistic regressi
on analysis. Outcomes were assessed immediately postvisit and at 2 wee
ks and 3 months. These included symptomatic improvement, functional st
atus, unmet expectations, satisfaction with care, clinician-perceived
patient difficulty, and health care utilization and costs. RESULTS: A
depressive or anxiety disorder was present in 146 (29%) of the patient
s. Independent predictors of a mental disorder included recent stress,
multiple physical symptoms (ie, 6 or more), higher patient ratings of
symptom severity, lower patient ratings of their overall health, phys
ician perception of the encounter as difficult, and patient age less t
han 50. Patients with depressive or anxiety disorders were more likely
to have unmet expectations postvisit (20% versus 8%, P < 0.001), be c
onsidered difficult (26% versus 11%, P < 0.0001), and report persisten
t psychiatric symptoms and ongoing stress even 3 months following the
initial visit. Psychiatric status was not associated with symptomatic
improvement, health care utilization, or costs. CONCLUSION: Simple cli
nical clues in patients with physical complaints identify a subgroup w
ho may warrant further evaluation for a depressive or anxiety disorder
. Such disorders are associated with unmet patient expectations and in
creased provider frustration. (C) 1997 by Excerpta Medica, Inc.