La. Lavery et al., INSTITUTIONALIZATION FOLLOWING DIABETES-RELATED LOWER-EXTREMITY AMPUTATION, The American journal of medicine, 103(5), 1997, pp. 383-388
PURPOSE: We are unaware of any report in the medical literature that h
as discussed risk factors for both mortality and discharge disposition
following lower extremity amputation (LEA). Our aim was to report ris
k factors associated with in-hospital mortality and the need for insti
tutional care in diabetics with LEAs. PATIENTS AND METHODS: We abstrac
ted data for every hospitalization for a LEA from January 1 to Decembe
r 31, 1993 in six metropolitan statistical areas in South Texas. Amput
ation level was categorized as foot, leg, or thigh. Discharge status c
ategories were: home, nursing home, rehabilitation facility, and death
. We used the Kaplan scale of cogent comorbidities to determine the re
lationship of 12 disease categories and their association with dischar
ge status. RESULTS: There were 1,043 LEAs in South Texas in 1993. Alth
ough only 2.3% of the population was admitted from an institutional ca
re facility, over 25% were discharged to one. Of the total population,
18.5% were discharged to a nursing home and 7.0% to a rehabilitation
facility, and 5.1% died within the period of hospitalization. We perfo
rmed a univariate analysis. Factors with a P <0.25 were included in a
stepwise logistic regression analysis with an alpha of 0.05. High leve
l (leg or thigh) amputation, peripheral vascular disease, male gender,
and absence of advanced locomotor impairment were associated with dis
charge to a rehabilitation facility. For discharge to a nursing home,
significant associations were found with: female gender, advanced age
(>65 years), single marital status, high level amputation, and advance
d cerebrovascular disease and locomotor impairment. Death following LE
A was strongly associated with female gender, high level amputation, a
dvanced renal disease, anemia, and congestive heart failure. CONCLUSIO
N: A significant number of patients either die or require long-term ca
re following a diabetes-related LEA, thus further adding to the burden
of this sequela. Several clinical parameters are significantly associ
ated with discharge status after this procedure. More prospective clin
ical research is needed to verify the associations and to clarify thei
r application in practice. (C) 1997 by Excerpta Medica, Inc.