A REVIEW OF TESTS FOR DETECTING A MONOTONE DOSE-RESPONSE RELATIONSHIPWITH ORDINAL RESPONSE DATA

Authors
CHUANGSTEIN C AGRESTI A
Citation
C. Chuangstein et A. Agresti, A REVIEW OF TESTS FOR DETECTING A MONOTONE DOSE-RESPONSE RELATIONSHIPWITH ORDINAL RESPONSE DATA, Statistics in medicine, 16(22), 1997, pp. 2599-2618
Citations number
50
Categorie Soggetti
Statistic & Probability","Medicine, Research & Experimental","Public, Environmental & Occupation Heath","Statistic & Probability","Medical Informatics
Journal title
Statistics in medicine → ACNP
ISSN journal
02776715
Volume
16
Issue
22
Year of publication
1997
Pages
2599 - 2618
Database
ISI
SICI code
0277-6715(1997)16:22<2599:AROTFD>2.0.ZU;2-P
Abstract
This tutorial reviews methods for testing independence between discret e levels of a dose and an ordered categorical response variable. The t ests are designed to be powerful for cases in which the response impro ves monotonically as dosage level increases. First, we show how to app ly some standard tests for doubly-ordered contingency tables. Then, we show how to construct tests as part of a model-building strategy. Oth er topics discussed include generalizations to stratified data, small- sample methods, and sample size and power considerations. (C) 1997 by John Wiley & Sons, Ltd.