ADENOMYOMATOUS POLYP OF THE UTERUS IN A PATIENT RECEIVING TAMOXIFEN

We report a case of adenomyomatous polyp that developed during treatme nt with tamoxifen for breast cancer, A 63-year-old Japanese woman was admitted complaining of atypical genital bleeding, Nine months earlier , she had undergone a modified radical mastectomy for cancer of her ri ght breast, estrogen receptor-positive stage I (T1NOMO), The administr ation of tamoxifen, 20 mg/day, was started immediately postoperatively . Pelvic examination after tamoxifen administration for 9 months revea led that the uterus was enlarged to the size of a fist, Transvaginal u ltrasonography and magnetic resonance imaging revealed a large solid m ass with multiple cystic areas in the uterine cavity. The pathological diagnosis of the tumor after total hysterectomy was typical adenomyom atous polyp, It was believed to have developed during tamoxifen admini stration.