EARLY NEURORADIOLOGIC EVIDENCE OF DEGENERATION IN MENKES DISEASE

Authors
GELLER TJ PAN Y MARTIN DS
Citation
Tj. Geller et al., EARLY NEURORADIOLOGIC EVIDENCE OF DEGENERATION IN MENKES DISEASE, Pediatric neurology, 17(3), 1997, pp. 255-258
Citations number
15
Categorie Soggetti
Clinical Neurology",Pediatrics
Journal title
Pediatric neurology → ACNP
ISSN journal
08878994
Volume
17
Issue
3
Year of publication
1997
Pages
255 - 258
Database
ISI
SICI code
0887-8994(1997)17:3<255:ENEODI>2.0.ZU;2-Q
Abstract
We report the case of an infant with Menkes' disease who presented wit h moderately abnormal neurologic findings at birth and with extraaxial bleeding in the posterior fossa, Early cerebellar atrophy and hypomye lination were evident on magnetic resonance imaging at 5 weeks of age. We suggest that neurodegeneration occurs earlier than has been previo usly reported and may be identifiable even in neonates. (C) 1997 by El sevier Science Inc. All rights reserved.