POSTPRANDIAL GLYCEMIA AFTER REGULAR AND LISPRO INSULIN IN CHILDREN AND ADOLESCENTS WITH DIABETES

We compared the postprandial blood glucose (BG)-levels following prepr andial regular insulin or lispro insulin before and after eating in ad olescents with diabetes. Lispro is a rapidly absorbed insulin analogue . Lispro insulin injected immediately before breakfast reduced the pos tprandial BG-rise significantly compared to the 20 min preprandially a dministered regular insulin (P < 0.01). Postprandial lispro injection resulted in similar BG values as the standard treatment with regular i nsulin 20 min preprandially. Conclusion Lispro insulin injected immedi ately before the meal leads to lower postprandial BG levels and stems to be an option for teenagers who use multiple preprandial insulin inj ections. Postprandial lispro administration could be a benefit in cert ain situations since it resulted in similar BG values to preprandial r egular insulin.