FATAL RHINO-ORBITAL-CEREBRAL ZYGOMYCOSIS

Rhinocerebral zygomycosis is usually an aggressive, fulminant and, at times, fatal disease most often affecting poorly controlled diabetics of all ages, We report the case of a 13-month-old white boy, a previou sly undiagnosed diabetic, He came to our hospital with recurrent epist axis, decreasing consciousness, and a small visible infection at the i nner canthus of the left eye Initial evaluation revealed that the pati ent was in diabetic ketoacidosis. Despite aggressive medical and surgi cal treatment, his condition deteriorated rapidly, including; the deve lopment of diabetes insipidus, and he died 4 days after admission, At autopsy, he was found to have fungal cerebritis (Rhizopus) with multip le areas of infarction and massive cerebral edema.