ROLE OF A SINGLE AMINO-ACID AT THE AMINO-TERMINUS OF THE SIMIAN-VIRUS-5 F2 SUBUNIT IN SYNCYTIUM FORMATION

Authors
ITO M NISHIO M KAWANO M KUSAGAWA S KOMADA H ITO Y TSURUDOME M
Citation
M. Ito et al., ROLE OF A SINGLE AMINO-ACID AT THE AMINO-TERMINUS OF THE SIMIAN-VIRUS-5 F2 SUBUNIT IN SYNCYTIUM FORMATION, Journal of virology, 71(12), 1997, pp. 9855-9858
Citations number
22
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
71
Issue
12
Year of publication
1997
Pages
9855 - 9858
Database
ISI
SICI code
0022-538X(1997)71:12<9855:ROASAA>2.0.ZU;2-C
Abstract
The fusion (F) protein of simian virus 5 (strain W3A) induced extensiv e cell fusion in BHK cells when expressed alone, while that of strain WR did not. Mutational analysis demonstrated that the fusing activity can be transferred to the WR F protein by a proline residue at positio n 22 of subunit W3A F2.