LEWIS ACID-CATALYZED DEPROTECTION OF P-METHOXYBENZYL ETHER

Authors
BOUZIDE A SAUVE G
Citation
A. Bouzide et G. Sauve, LEWIS ACID-CATALYZED DEPROTECTION OF P-METHOXYBENZYL ETHER, Synlett, (10), 1997, pp. 1153
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
10
Year of publication
1997
Database
ISI
SICI code
0936-5214(1997):10<1153:LADOPE>2.0.ZU;2-3
Abstract
The p-methoxybenzyl protecting group was readily removed from alcohols and phenols using catalytic amounts of AlCl3 or SnCl2 . 2H(2)O in the presence of EtSH at room temperature. Under these mild conditions oth er protecting groups such as methyl and benzyl ethers, p-nitrobenzoyl esters, TBDPS ethers and isopropylidene acetal were unchanged.