The objective of this study wets to determine whether nonenhancing pan
creatic lesions are accurate in estimating pancreatic necrosis, Twenty
-six consecutive abdominal computed tomography (CT) examinations perfo
rmed over a 3-year period that met the CT criteria ria for pancreatic
necrosis were reviewed. Follow-up CTs in three of 26 patients demonstr
ated pancreatic enhancement, indicating viable parenchyma, within the
previously nonenhancing regions. All three patients had undergone surg
ical debridement in that area. Twenty-three cases demonstrated either
no change or enlargement of the nonenhancing pancreatic lesions. Follo
w-up ranged from 2 week to 26 months. While CT is accurate in diagnosi
ng pancreatic necrosis, lack of enhancement in CT may occasionally ove
restimate the extent of necrosis. Nonenhancing, viable but at-risk tis
sue may be present adjacent to frankly necrotic tissue. Surgical debri
dement may facilitate recovery of this viable tissue, which may enhanc
e normally on follow-up CT. (C) Elsevier Science Inc., 1997.