EXPRESSION OF GLYCOPROTEIN GP43 IN STAGE-SPECIFIC FORMS AND DURING DIMORPHIC DIFFERENTIATION OF PARACOCCIDIOIDES-BRASILIENSIS

Authors
MATTAR R AZEVEDO MO PEREIRA M JESUINO RSA SALEMIZACC SM BRITO WA GESZTESI JL SOARES RBA FELIPE MSS SOARES CMA
Citation
R. Mattar et al., EXPRESSION OF GLYCOPROTEIN GP43 IN STAGE-SPECIFIC FORMS AND DURING DIMORPHIC DIFFERENTIATION OF PARACOCCIDIOIDES-BRASILIENSIS, Journal of medical and veterinary mycology, 35(5), 1997, pp. 341-345
Citations number
21
Categorie Soggetti
Mycology
Journal title
Journal of medical and veterinary mycology → ACNP
ISSN journal
02681218
Volume
35
Issue
5
Year of publication
1997
Pages
341 - 345
Database
ISI
SICI code
0268-1218(1997)35:5<341:EOGGIS>2.0.ZU;2-1
Abstract
Expression of the 43 kDa glycoprotein (gp43) was analysed in several P aracoccidioides brasiliensis isolates. Using one- and two-dimensional analysis of crude cellular extracts, it was shown that protein express ion in yeast and mycelium was dependent on the isolate analysed. In tw o strains, in both yeast and mycelium cells, gp43 was present, whereas expression was restricted to the yeast phase of two other strains. Th e clinical implications of this phase-specific gp43 expression are unc ertain.