VIRAL FACTORS DETERMINING ROTAVIRUS PATHOGENICITY

Authors
DESSELBERGER U
Citation
U. Desselberger, VIRAL FACTORS DETERMINING ROTAVIRUS PATHOGENICITY, Archives of virology, 1997, pp. 131-139
Citations number
56
Categorie Soggetti
Virology
Journal title
Archives of virology → ACNP
ISSN journal
03048608
Year of publication
1997
Supplement
13
Pages
131 - 139
Database
ISI
SICI code
0304-8608(1997):<131:VFDRP>2.0.ZU;2-J
Abstract
The pathogenicity of rotaviruses depends on multiple viral and host fa ctors. Evidence is presented for the involvement of a number of viral genes (coding for structural and non-structural proteins) in the abili ty of the virus to cause diarrhoea. Different genes are important in d ifferent rotavirus-host systems suggesting that there is no single vir al pathogenicity factor.